李海涛教授

发布时间:2012-10-17  访问次数:5583

李海涛教授

111实验室网址:www.jsnulht.com

  

  

  

  

名:李海涛

出生年月:196904

学位学历:博士

职称:教授

学科专业:生物物理化学

E-maillh0002@gmail.com


个人简历

教育背景和工作简历

19945- 19998: 瑞典Linköping(林雪平)大学化学物理专业获工学博士学位

19999- 200010:以色列魏兹曼科学院博士后

200011- 20024:德国多特蒙德大学物理系博士后

20025- 20129:英国剑桥大学化学系PI

20129-至今:江苏师范大学江苏特聘教授

【研究领域和兴趣】

1. 单分子超高灵敏度荧光显微镜的发展

2. 与癌症高度相关的端粒和端粒酶的深入研究

3. 石墨烯碳分子筛以及在环境科学中的应用。

4. 能纳米传感器构建及其在生物分析中的应用。

【承担的主要科研项目】

序号

项目名称

项目级别

项目来源

项目号

经费

项目排序

起止日期


New microscopy of Two color coincidence detection

国家级

英国生物技术与生物科学研究理事会基金(BBSRC


100 000英镑

合作主持



Self-Assembled from Nanometer-Sized Protein/DNA Complexes Cambridge Nano IRC

国家级

EPSRC


24万英镑

合作主持



A Matter of Life and Death: Dissecting the Assembly, Structure and Function of Human Telomerase

国家级

the Leverhulme Trust


25万英镑

合作主持



TheraEDGE: An integrated platform enabling Theranostic applications at the point of primary care

国家级

欧盟项目


800 万欧元

合作主持



使用单分子荧光显微镜在微流体中快速检测端粒酶RNA

国家级

国家自然科学基金项目


80万人民币

主持


【代表性论文】

1A single-bead telomere sensor based on fluorescence resonance energy transfer, Haitao Li et al. Analyst, 2016, 141: 3033-3040

2. Highly Reproducible Ag NPs/CNT-Intercalated GO Membranes for Enrichment and SERS Detection of Antibiotics, Haitao Li et al. ACS Applied Materials & Interfaces 2016, 8, 28180-28186.

3. Design and Development of a Telomere Sensor Based on Fluorescence Energy Transfer, Haitao Li. Biophysical Journal, 2016, 110(3): 639.

4. 饮用水中抗生素残留检测方法研究进展, 李海涛等,化学通报, 2016, 79(3): 213-219

5. Highly selective and sensitive surface enhanced Raman scattering nanosensors for detection of hydrogen peroxide in living cells, Haitao Li et al. Biosens. Bioelectron., 2016, 77: 292298

6. Silver nanoparticles on cotton swabs for improved surface-enhanced Raman scattering, and its application to the detection of carbaryl, Haitao Li et al. Microchim. Acta, 2016: 1-7

7.单分子荧光技术在端粒、端粒酶研究中的应用, 李海涛等,化学进展, 2014, 26(12): 1987-1996

8. Single molecule fluorescence under conditions of fast flow. LiHaitao et al. Ana Chem2011; 84(1):179-85

9. Single-Molecule analysis of human Telomerase monomer, LiHaitao et al, Nature Chemical Biology 4 287-289 2008.   

10. Two-color fluorescence analysis of individual virions determines the distribution of copy number of proteins in herpes simplex virus particles LiHaitao et al. Biophysical Journal 93 1329 –1337, 2007.

11. Evidence for Resonance Optical Trapping of Individual Fluorophore-Labeled Antibodies Using Single Molecule Fluorescence Spectroscopy, LiHaitao et al. J. Am. Chem. Soc., 128 (17), 5711 -5717, 2006.

12. Analysis of Human Telomerase Activity and Function by Two Color Single Molecule Coincidence Fluorescence Spectroscopy, LiHaitao et al. J Am Chem Soc. Apr 19;128(15):4992-5000. 2006.

13Characterization of a single molecule DNA switch in free solution,LiHaitao et al. J Am Chem Soc. 128, 11423-32. 2006.

14. Macroscopic 2D Networks Self-Assembled from Nanometer-Sized Protein/DNA Complexes, LiHaitao et al. Nano Lett., 6 (3), 365 -370, 2006.

15. Probing Single Molecule Intramolecular Dynamics in Solution by Two-Color Filtered Ratiometric Fluorescence Correlation Spectroscopy, LiHaitao et al. Proc. Natl. Acad. Sci. USA 101, 14425-14430, 2004.

16. Fluorescence Studies of Single Biomolecules, LiHaitao et al, Biochem. Soc. Trans.32(5):753-756, 2004.

17. Studies on the Structure and Dynamics of the Human Telomeric G-Quadruplex by Single Molecule FRET, LiHaitao et al. Proc. Natl. Acad. Sci. USA 100,14629-14634 (2003).

18. Ultrasensitive Coincidence Fluorescence Detection of Single DNA Molecules. LiHaitao et al. Anal. Chem.; 75(7); 1664-1670 (2003).

19. Identification of a new RNA•RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenital point mutation. LiHaitao et al. Nucleic Acids Res. 31, 6509-6515 (2003).


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